Jo Henderson (May 10, 1934 – August 6, 1988) was an American stage, film and television actress.

[2] She started her professional career in New York City, and was mainly active on stage, appearing both in Broadway and Off-Broadway works, as well as in regional playhouse productions.

[2] In 1976, Henderson won an Obie Award for Distinguished Performance by an Actress for Ladyhouse Blues.

[1][2] In 1984, she received a Tony Award nomination for Best Featured Actress in a Play thanks to her performance in Play Memory, losing to Christine Baranski.

[2][3] Also active in films and on television, Henderson died in traffic collision in Chinle, Arizona, at the age of 54.