Krajewski, who lived in Port Richmond and whose district included much of Lower Northeast Philadelphia, began her political career as a Republican committeeperson.

One of a faction of conservative white Democrats who represented working-class Philadelphia neighborhoods and were sometimes described as "Rizzocrats," she was known for her loyalty to her supporters and her skill at political maneuvering and was often described as "tough" and "a fighter.

Krajewski was, prior to her election, an active union official who served as the president of Local 1660-School Board Employees, District Council 33, and the American Federation of State, County and Municipal Employees’ Union.

[6] She played a crucial role in 1999 ensuring that the owners of condemned houses in Wissinoming were fully compensated.

[7] She persuaded Mayor Rendell to revisit a sewer construction project from 1996-97 which homeowners believed caused structural issues in their homes, coordinated with state representatives securing state funds for the homeowners, and provided ongoing support to the affected residents until the situation was resolved.