Joe DePre (born December 19, 1947) is an American former professional basketball player.

He played three seasons as a shooting guard in the American Basketball Association (ABA), all as a member of the New York Nets (1970–73).

He was drafted in the second round (29th overall) of the 1970 NBA draft from St. John's University by the Phoenix Suns, but he never played for them.

DePre played in the Eastern Basketball Association (EBA) for the Wilkes-Barre Barons, Long Island Sounds and Long Island Ducks from 1972 to 1978.

This biographical article relating to a United States basketball player, coach, or other figure born in the 1940s is a stub.