Joe Keyes (c. 1907 – November 1950) was an American jazz trumpeter during the 1930s and 1940s with the band of Bennie Moten, Count Basie, and Hot Lips Page.
Following Moten's death in 1935, and together with several other members of the band, he joined the Count Basie Orchestra, but left in 1937.
He then worked in the band led by "Hot Lips" Page, and recorded with guitarist Eddie Durham and saxophonist Buster Smith.
Around 1941, he played briefly with both Fletcher Henderson and Fats Waller, and in 1943 with Claude Hopkins.
His body was found floating in the Harlem River in New York City on November 6, 1950.