Joe Perham (October 26, 1932 – August 29, 2013) was an American humorist, known for his "Down East Maine" humor.

[1] Sample has described Perham as a "seriously funny guy with a professionally honed native wit, which inevitably leaves his audiences weak from laughter.

While at Colby, Perham was a member of Phi Beta Kappa society, and earned money by working in the feldspar mines for three summers and running a jackhammer the fourth summer for a construction firm, earning 68 cents an hour in the mine and $2.00 an hour running a pneumatic drill.

He has appeared in two films: as a mill inspector in Graveyard Shift (1990), based on the novel by Stephen King, and with his wife Margaret Perham (Grover), in Bed & Breakfast (1992), with Roger Moore and Colleen Dewhurst.

[2] Perham retired following his diagnosis with Alzheimer's disease, and lived in West Paris, Maine with his wife Margaret, who often appeared in his material, until his death in August 2013.