At Jena he was director of a health institute and subdirector of maternity hospital services.
Known as an outstanding clinical teacher, one of his better-known students was Adam Elias von Siebold (1775–1828).
He was a physician to the Weimar Ducal Court, in particular Anna Amalia and Carl August of Saxe-Weimar-Eisenach.
In 1787 he became editor of the first obstetric-gynecological journal, Archivs für Geburtshilfe, Frauenzimmer und Neugeborener Kinder Krankheiten.
He also published works in the fields of pharmacology and pediatrics, and was the author of a treatise on the history of tetanus.