Johann Christian von Mannlich (2 October 1741 – 3 January 1822) was a German painter and architect.
Under Christian IV's successor, Charles II August, Duke of Zweibrücken, he was general director of buildings, in which capacity he was responsible for the design and construction of Schloss Karlsberg near Homburg, besides forming the duke's picture collection.
When the castle was destroyed by French Revolutionary forces on 28 July 1793, von Mannlich was able to rescue not only the picture collection but also the library and quantities of furniture, tapestries and other items.
The picture collection eventually reached Munich via Mannheim, where it formed the basis of the collections of the Alte Pinakothek and where von Mannlich was the director of galleries for Maximilian I Joseph, King of Bavaria.
As a teacher, von Mannlich counted among his pupils the pastellist Anna Margarethe Geiger.