Soon Heine had his own workshop where he manufactured artificial limbs, stretching beds, wheelchairs and other orthopedic appliances and offered them for sale.

In 1807 Heine published his Systematic Index of surgery instruments, bandages and machines, a kind of catalogue for physicians,[1] with later editions in 1811 and 1827.

The Bavarian crown prince awarded him an order for his merits ("Goldene Zivil-Dienst-Medaille") and even Johann Wolfgang von Goethe knew Heine's publications and included them in his library.

He got to know "Operateur Heine" at the dinner table of Grand Duke Karl August and invited him to his private home.

When he started to cure non-orthopedic diseases he provoked conflicts with the rest of the Würzburg doctors, which put an end to a long period of successful co-operation.