In 1689, he became court painter to Count Hermann Jakob Cern.
[2] Johann Rudolf Byss is credited with bringing the Netherlandish and Italian classic styles to the art sphere in Prague.
[2] Johann Rudolf Byss obtained the citizenship of Prague in 1692.
[2] He is known for religious works and flower still lifes, and his pupil was Johann Adalbert Angermeyer.
In 1713, he painted the ceiling fresco of the main staircase at Schloss Weissenstein.