Johannes Schenck von Grafenberg (Latin: Ioannes Schenckius) (June 20, 1530 – November 12, 1598) was a German physician.
He studied at Tübingen, and was later a physician to the city of Freiburg im Breisgau.
He was the father of physician Johann-Georg Schenck von Grafenberg (died 1620).
Johannes Schenck was one of the more influential authorities on medicine during the late Renaissance Era.
Schenck's best-known written work was Observationum medicarum rariorum, libri VII, which was a seven-volume compendium that described pathological conditions concerning all the parts of the human body.