In 1821 he joined Edward Grainger, a teacher of anatomy, as lecturer on medicine at the school then being founded by the latter in Webb Street, a significant institution of the time.
In 1826 he joined James Risdon Bennett in founding another school in Little Dean Street, Soho, and for some time lectured in both places.
He published Practical Illustrations of the Scarlet Fever, Measles, Pulmonary Consumption (London, 1818), which added to his reputation.
Armstrong's own views changed in relation to typhus, which he in his earlier works asserted to be contagious, but in his later memoirs (The Lancet, 1825) attributed to a malarial origin.
[1] Armstrong wrote also: In 1811 he married Sarah, daughter of Charles Spearman, by whom he left a family, including a son John, who became bishop of Grahamstown.