Sir John Arundell (c. 1500 – 1557), was MP for Cornwall in 1554.
He was the eldest son of John Arundell (1474–1545), who was termed "the most important man in the county", and his first wife, Lady Eleanor Grey, daughter of Thomas Grey, 1st Marquis of Dorset and Cecily Bonville, 7th Baroness Harington.
The politician Thomas Arundell of Wardour Castle, who was executed for treason in 1552, was his younger brother.
John was arrested and imprisoned with his brother, but never stood trial.
He married Elizabeth Dannett, daughter of Sir Gerald Dannett of Dannett's Hall, Bromkinsthorpe, Leicestershire and had issue: The memorial brass commemorating John and Elizabeth at St Mawgan in Pydar is lost, but a fragment still remains.