Ashworth was born on 8 July 1813 at the hamlet of Cutgate near Rochdale, the eighth child of his parents, who were poor woollen weavers.

He has himself told the story of his mother manufacturing a 'bishop' (pinafore) for him out of a pack-sheet, from which all her exertions could not wash away the indelible word 'Wool,' which therefore formed his breastplate.

He was a vigorous preacher of the orthodox type, and understanding the people's way of life, and speaking a language which they understood, he gathered a great congregation.

He was a liberal in politics, a staunch teetotaller, and an uncompromising advocate for the Maine Law and the observance of the Sunday after a rigid puritanical fashion.

He visited the United States and the Holy Land, and for many years had a busy life as preacher, manufacturer, lecturer, and author.