D'Agostino is a senior advisor to Coinbase[1] and Chairman of US Asset Management Committee for the Department for International Trade.

[6][7] In 2021, Mr. D'Agostino co-founded the Alternative Investment Management Association (AIMA) Digital Asset Working Group.

[6][14] After graduating from Harvard Business School, D'Agostino joined the New York Mercantile Exchange where he helped transition the floor to electronic trading.

The book was published in 2008 in United Kingdom with a slight variation in the title as Rigged, The True Story of a Wall Street Novice who Changed the World of Oil Forever.

[12] D'Agostino was mentioned in a book by Wall Street journalist Leah McGrath Goodman, titled The Asylum: Inside the Rise and Ruin of the Global Oil Market published in 2011.

[27] At the 2018 World Capital Markets Symposium, when asked to comment on the sustainability, diversity and equality in the finance industry, D'Agostino remarked "It doesn't matter if we are ready or not, the future is decidedly female" which received considerable media interest.

[28] In June 2018, John D'Agostino and Nouriel Roubini led a discussion on cryptocurrencies at the Battle of the Quants in New York.

[29] In contrast to Roubini, D'Agostino remained neutral on cryptocurrencies and the blockchain ecosystem and its viability in the short-term, and cautiously optimistic in the long-term.