[1] South began to attend the practice of St. Thomas's Hospital within a few weeks of leaving school, and on 18 February 1814 he was apprenticed to Henry Cline the younger, then a surgeon there.
He attended Sir Astley Cooper's lectures on anatomy, and met in 1813 Joseph Henry Green, a fellow apprentice and lifelong friend.
As a reward the Swedish Horticultural Society at Stockholm, at the instigation of his friend Retzius, awarded to its Linnæan medal of bronze.
Recognised as a Latinist, he was selected to examine articled pupils in Latin before they were apprenticed to the Royal College of Surgeons of England.
[1] Besides tracts on surgical and religious subjects and the articles on the "Zoology of the Invertebrata" in the Encyclopædia Metropolitana, South wrote:[1] He translated:[1] The last twenty years of South's life were spent in gathering material for a history of English surgery; it was edited by D'Arcy Power in 1886 as Memorials of the Craft of Surgery.
After her death, in 1864, he married, the following year, Emma, daughter of John Louis Lemmé of Antwerp and London, the niece of his friend J. H. Green.