John Freeman Loutit

[1] His candidature citation read: Distinguished for his experimental studies of tissue transplantation after lethal doses of ionising radiation.

Skilful experiments led Loutit to form the opinion that, contrary to the prevailing view, the survival of irradiated mice after the implantation of haematropoietic tissue was due to colonization by living cells.

Loutit has further shown that a substantial proportion of mice with leukaemia can be cured by whole body irradiation followed by the grafting of bone marrow cells.

Earlier, he separated the mechanisms of origin of congenital haemolytics and acquired icterus and developed a practical method of increasing the storage time of bllod for transfusion.

Loutit's work is fundamental to an understanding of the mechanism and repair of radiation injury and has important bearings on immunology and the study of leukaemias.