John George II (17 November 1627 – 7 August 1693) was a German prince of the House of Ascania and ruler of the principality of Anhalt-Dessau from 1660 to 1693.

The Hague, 10 February 1637 – d. Schloss Oranienbaum, 3 November 1708), daughter of Frederick Henry, Prince of Orange.

John George made his military career in the service of the Prussian army; the Elector Frederick William named him a Generalfeldmarschall in 1670.

After France invaded Frederick William's Duchy of Cleves, John George negotiated a treaty in Vienna in June 1672 between Leopold I, Holy Roman Emperor, and Frederick William, by which each pledged to provide 12,000 troops to uphold the borders of the Peace of Westphalia in the face of French aggression.

While campaigning against the French for control of Alsace in 1674, most of Frederick William's army went into winter quarters in Franconian Schweinfurt.