John George of Monferrat (20 January 1488 – 30 April 1533) was the last Marquis of Montferrat of the Palaeologus-Montferrat family.

John George was Bishop of Casale when his nephew Boniface IV, Marquis of Montferrat unexpectedly died in 1530 without an heir.

In a desperate attempt to produce an heir, he married the 41-year-old Julia, daughter of Frederick IV of Naples, on 21 April 1533.

After a Spanish occupation of 3 years, Montferrat came under Federico II Gonzaga, Duke of Mantua, who had married his niece Margaret Paleologa in 1531.

John George had an illegitimate son, Flaminio, from whom the Paleologo-Oriundi line descends and is extant today.