John Henry Comstock (February 24, 1849 – March 20, 1931) was an eminent researcher in entomology and arachnology and a leading educator.

In 1872, in the absence of a professor in entomology, students submitted a petition requesting that Comstock be given permission to deliver a course of lectures upon "Insects Injurious to Vegetation".

Anna also studied entomology: she earned a degree and worked with her husband to write and illustrate books and articles on the subject.

Between 1879 and 1881 he became the chief Entomologist of the USDA in Washington, D.C.[1] In 1882 Comstock returned to Cornell as professor of Entomology and Invertebrate Zoology.

[10] Comstock retired from teaching and administrative work in 1914 at age 65, but continued to do research and write.

[1][10] Comstock, through his own work and that of his wife and students, had a significant influence in the development of entomology departments throughout the United States.