Sherwin was sent to study in London, first under John Astley, and then for three years under Francesco Bartolozzi – for whom he is believed to have executed a large portion of the plate of Clytie, after Annibale Carracci, published as the work of his master.
Establishing himself in St James's Street as a painter, designer and engraver, he attained popularity and began to mix in fashionable society.
His drawing of the "Finding of Moses", a work of but slight artistic merit, which introduced portraits of the princess royal of England and other leading ladies of the aristocracy, hit the public taste, and, as reproduced by his burin, sold largely.
[2] Sherwin died in extreme penury on 24 September 1790 – according to George Steevens, the editor of Shakespeare, at The Hog in the Pound, an obscure alehouse in Swallow Street, or, as stated by his pupil J.T.
Such of his plates as the "Holy Family" after Nicolas Poussin, "Christ Bearing the Cross" after Murillo, the portrait of the marquis of Buckingham after Thomas Gainsborough and that of Pitt occupy a high place among the productions of the English school of line-engravers.