He pitched a story for Doctor Who, The Doomsday Contract, while Adams was script editor of the series, which was never made at the time but eventually became an audio play adapted by Nev Fountain and produced by Big Finish Productions.

A pilot episode of the show was recorded under this name in mid-1990, with Lloyd hosting alongside team captains Ian Hislop and Paul Merton.

His first new TV series for 14 years, QI starring Stephen Fry (2003 - 2016), Sandi Toksvig (from 2016 - present) and Alan Davies, began on 11 September 2003 at 10pm on BBC Two for a run of 12 episodes.

Lloyd has presented the radio series The Museum of Curiosity (2011), which he co-created with producers Richard Turner and Dan Schreiber and former co-host Bill Bailey.

In December 2011, Lloyd appeared as captain of the winning Trinity College, Cambridge, team on the Christmas University Challenge.

[7] In August 2014, Lloyd was one of 200 public figures who were signatories to a letter to The Guardian opposing Scottish independence in the run-up to September's referendum on that issue.