He matriculated at Pembroke College, Oxford on 29 March 1705, aged 17, and was admitted at Middle Temple in 1705.

[2] Neale was returned as a Whig Member of Parliament for Chipping Wycombe at a by-election on 8 February 1722.

At the 1734 general election Neale was defeated by John Bird, a local merchant who stood on the anti-excise platform.

Neale recovered his seat in a contest at a by-election on 15 February 1737, but the election was declared void on 22 March 1737.

[2] His daughter Frances married Sir John Turner, 3rd Baronet and inherited Cherington Park.