John Neville, born 17 November 1493, was the eldest son of Richard Neville, 2nd Baron Latimer, by Anne Stafford, daughter of Sir Humphrey Stafford (died 1486) of Grafton, Worcestershire, and Katherine Fray (12 May 1482), the daughter of Sir John Fray, Chief Baron of the Exchequer, by Agnes Danvers (d. June 1478), the daughter of Sir John Danvers (died c. 1448).
[3] In 1513 he served in King Henry VIII's French campaign, and was knighted after the capture of Tournai.
Neville was appointed to the Council of the North in that year, and signed the letter petitioning Pope Clement VII to grant Henry VIII a divorce from Catherine of Aragon.
[citation needed] He represented the insurgents, however, in November 1536 at the conferences with the royal leaders, and helped to secure the amnesty.
[citation needed] Neville married firstly, by 1520, Dorothy (d. 7 February 1527), daughter of Sir George de Vere by Margaret Stafford, and sister of John de Vere, 14th Earl of Oxford, by whom he had a son and a daughter:[6] Neville married secondly, by licence dated 20 June 1528 Elizabeth (d. before 1533), daughter of Sir Edward Musgrave of Hartley, Westmorland, and Edenhall, Cumberland, by whom he had no issue.