John Nixon (1733 – December 31, 1808) was a financier and official from Philadelphia who served as a militia officer in the American Revolutionary War.

John Nixon was among those who signed the non-importation agreement of 1765, from which time on he was one of the leaders of the patriot cause in Philadelphia.

In the following December, Nixon, having in the meantime succeeded to the chief command, reinforced Washington at Trenton and participated in the battle of Princeton.

In 1776 Nixon served on the navy board and in 1778 he spent the winter at Valley Forge.

He was also one of the founders of the Bank of North America, established in 1783, and its president from 1792 until his death, which occurred December 31, 1808.