John Odenheimer Deshong (September 6, 1807 – May 28, 1881) was an American businessman and banker in Chester, Pennsylvania.

[2] As a young adult, Deshong established a general store at Fourth and Market Street.

Deshong turned his attention to financial affairs, using his capital as a dealer in commercial paper.

[7] The Deshong mansion was built in 1850 on 22 acres off Edgemont Avenue in the Greek Revival Italianate style .

Their daughter, Louise was a pioneer in photography by women and married the shipbuilder and naval architect Jonathan Edwards Woodbridge.