[1] He was a son of John Oothout (1739–1804) and Magdalena (née van der Water) Oothout (1754–1826), a daughter of William van der Water.

His paternal grandparents were Jan Oothout and Catalyntje (née Van Deusen) Oothouth.

His aunt, Elizabeth Oothout, was the wife of John Tobias Ten Broeck (a grandson of Albany mayor Dirck Wesselse Ten Broeck).

[2] He was educated in the office of Robert Lenox, "one of the most prominent merchants of that time.

[2] Together, they were the parents of:[5] Oothout died in New York City on January 28, 1858.