There were plans to seize Salisbury, Newcastle, York and Winchester and to instigate smaller uprisings in Nottinghamshire and Cheshire.
As the New Model Army garrison in Winchester was reinforced shortly before the uprising, plans to attack it were abandoned.
Penruddock, along with Sir Joseph Wagstaffe and Hugh Grove, organised and led the Royalist uprising in the West.
The next morning, leading his followers out of Salisbury, Penruddock headed westwards through Blandford, Sherborne and Yeovil, hoping to pick up more supporters.
By 14 March, his exhausted group had reached South Molton in Devon, where, after a three-hour street fight, it was defeated by a single New Model Army troop of horse under Captain Unton Crook.