After his mother's death, he inherited the family estates in Essex, and the baronial title.
In 1486, he was appointed caretaker and chief judge of the royal forests south of Trent, together with Sir Reginald Bray.
In 1495, Radcliffe was accused of plotting to instal the Yorkist claimant Perkin Warbeck on the throne.
[1] Radcliffe married, first (before 12 March 1476) Anne, sister of Sir Richard Whethill of Calais; his second wife is usually supposed to have been Anne, daughter of Edward Hastings, 2nd Baron Hastings, who in 1507, if not earlier, became the wife of Thomas Stanley, 2nd Earl of Derby (died 1521) and died in 1550.
The attainder was removed in favour of his son Robert, afterwards first Earl of Sussex, by letters patent of 25 January 1506, confirmed by an Act of Parliament in 1509.