John Sappington (October 1847 – February 10, 1905) was a physician and politician from Maryland.

John Sappington was born in October 1847 in Darlington, Maryland, to Mary (née O'Neal) and John Sappington.

He attended the University of Virginia and started to study medicine.

[1][2] Sappington worked as a physician and had a medical practice.

He later married Rosa Jacobs of Bel Air.