John William Huffman (July 21, 1932 – May 14, 2022) was a professor of organic chemistry at Clemson University who first synthesised novel cannabinoids.
"[5] In the late 2000s, two of Huffman's cannabinoid compounds were found in street drugs K2 and Spice being sold in Germany as marijuana alternatives.
[7] As JWH-018 is more potent and easy to make, Huffman believes it is a more widely used synthetic cannabinoid of the JWH series.
[8] In the US, the states of Kansas, Georgia, Alabama, Tennessee, Missouri, Louisiana, Mississippi, Arkansas, and New York banned K2, herbal incense.
Law enforcement officials in Canada asked Huffman to serve as a consultant and expert witness.