A Raleigh, North Carolina, native, Wall was chosen with the first overall pick of the 2010 NBA draft by the Washington Wizards after playing one year of college basketball for the Kentucky Wildcats.

[7] The death of his father caused Wall to frequently reject the authority of adults and act up, occasionally fighting, mostly in middle school.

Coach Levi Beckwith worked with Wall, first to stop demeaning his teammates for missed layups, and later to improve his facial expressions and general demeanor.

[3] On the heels of his second sophomore year of high school, in the summer of 2007, Wall was invited to the prestigious Reebok All-American Camp in Philadelphia; there, he distinguished himself by scoring 28 points against a team that featured future lottery pick Brandon Jennings.

[7] In 2008, Wall played in the Elite 24 Hoops Classic, at which he scored 10 points and won co-MVP honors alongside Dominic Cheek, Maalik Wayns, and Lance Stephenson.

[11] As a fifth-year senior in 2009, Wall averaged 19.7 points, nine assists, and over eight rebounds for Word of God Christian Academy[12] and was ranked one of the best high school basketball players in the class of that year.

[13] He led the Holy Rams basketball team all the way to the North Carolina Class 1A state championship; they were ultimately defeated by United Faith Christian Academy 56–53.

[14] He was selected to participate in the 2009 Nike Hoop Summit in Portland, Oregon; he scored 13 points to go along with 11 assists and five steals at the high-profile event.

[20] Because Wall was a fifth-year high school senior in 2009 and would turn 19 by the end of the year, some sources argued that he would be eligible for the 2009 NBA draft.

[22] On April 7, 2010, Wall announced that he would forgo his final three seasons of collegiate eligibility and enter the 2010 NBA draft, where he was expected to be the first overall selection for the Washington Wizards.

[26] Wall was named the Most Valuable Player of the 2010 Las Vegas Summer League,[27] averaging 23.5 points, 7.8 assists, 4.0 rebounds and 2.5 steals in 32.3 minutes per game.

[35] In a road game against the Los Angeles Lakers on March 22, Wall recorded 24 points and a career-high 16 assists in a win.

On July 31, 2013, Wall, labeled by the Wizards as a designated player, signed a five-year contract extension worth approximately $80 million.

[38] On January 22, 2014, Wall recorded his second career triple-double with 28 points, 11 rebounds and 10 assists in a 113–111 overtime loss to the Boston Celtics.

[40] During All-Star weekend, he became the first in Washington franchise history to win the Slam Dunk Contest after fans voted him the Dunker of the Night.

[45] Wall averaged 19.3 points, 8.8 assists, and 4.1 rebounds on the season as the Wizards finished as the fifth seed in the East and qualified for the playoffs for the first time in six years.

Following the game, Wall dedicated the win to his close friend, six-year-old Damiyah Telemaque-Nelson, who had died of cancer earlier that day.

[48] On January 22, 2015, he was named an Eastern Conference starter for the 2015 NBA All-Star Game, earning his first starting gig after garnering 886,368 votes.

[60] On January 16, he recorded a season-high 36 points, 13 assists and 7 steals against the Boston Celtics, but missed a potential tying layup at the buzzer, as the Wizards were defeated 119–117.

[67] Following off-season surgery on both knees, Wall was rested in the second of back-to-back night games early on in the 2016–17 season, as a way of limiting his minutes.

[85] On April 16, Wall scored a playoff career-high 32 points in a 114–107 win over the Atlanta Hawks in Game 1 of their first-round series.

[94] The next day, he scored 17 of his 23 points in the second half and overtime, and tied a season high with 16 assists in the Wizards' 119–113 victory over the Brooklyn Nets.

[101] On November 26, 2018, in a 135–131 overtime win over the Houston Rockets, Wall passed Wes Unseld for third place on the franchise career scoring list.

[108][109] On March 22, 2021, Wall logged his eighth career triple-double with 19 points, 11 rebounds and 10 assists in a 117–99 win over the Toronto Raptors, ending the team's 20-game losing streak.

[112] In 2021–22, Wall and the Rockets reached a mutual decision for him not to play, as the team was rebuilding and developing young guards Kevin Porter Jr. and Jalen Green.

[115] Wall made his debut with the Clippers on October 20, where he put up 15 points, four rebounds, and three assists in a 103–97 win over the Los Angeles Lakers.

[118] In July 2014, Wall was selected as a member of the United States camp roster to compete for the 2014 FIBA Basketball World Cup team.

[119] Due to off-season knee surgery, Wall withdrew his name from consideration for USA Basketball's 2016 Rio Olympics team.

The two-acre property, which has eight bedrooms, six garages, and 17,980 square feet, was selected to accommodate Wall's mother, siblings, and guests.

[137] In November 2020, Wall became a co-owner of the South East Melbourne Phoenix, a team in the Australian National Basketball League.