John Lewis "Hurri" "Sugar" Cain (November 17, 1908 – August 18, 1977) was an American football player, coach of football, baseball, and tennis, and college athletics administrator.

He played college football at the University of Alabama, where he was a three-time All-American and a member of the 1930 national championship team that won the Rose Bowl.

In 1947, Cain moved to the University of Mississippi to serve as backfield coach for the football team under Johnny Vaught.

Cain was elected to the College Football Hall of Fame as a player in 1973.

Cain died of leukemia, on August 18, 1977, at Baptist Hospital in Memphis, Tennessee.