Jonathan Newsome (born January 22, 1991) is an American professional football defensive end.

As a senior, Newsome was named All-Ohio second-team while playing for coach Ted Ginn Sr. at Glenville High School in Cleveland.

In week 9, playing against the New York Giants, he recorded seven tackles, two sacks, and one forced fumble.

In game 2 of the 2017 season, on July 1, 2017, Newsome recorded an interception in the Roughriders' 43–40 loss to Winnipeg.

[10] In nine games with Ottawa, Newsome recorded 13 tackles, four sacks, an interception, and a forced fumble.

On December 20, 2018, Newsome signed a one-year extension with Ottawa; in the 2018 postseason and in 2019 training camp the team experimented with a designated package of plays for Newsome, moving him around the field to a variety of linebacker positions.

On September 13, 2019, he recorded two defensive tackles and had a key sack on third and goal against the Redblacks, his former team.