[2] After starting out at Liverpool Montevideo he moved to Porto in Portugal, going on to appear in 155 competitive matches over eight seasons and win 11 major titles, including five Primeira Liga championships and the 2011 Europa League.

On 31 August 2006 he was transferred on loan to FC Porto in Portugal,[3] appearing in 18 games in his first season as the northerners won a second consecutive Primeira Liga; the move was made permanent on 1 July 2007, with the player signing a five-year contract.

In the 2011–12 season, under new manager Vítor Pereira, Fucile lost his importance in the first team – after Cristian Săpunaru's injury, central defender Maicon was chosen as his successor.

[4] In mid-January 2012 he moved on loan to Brazil's Santos FC in a one-year-long deal,[5] being released by his parent club exactly one year later but re-admitted in March 2013.

[13] He returned to his country on 29 October 2020 after 11 months of inactivity, signing a short-term contract at Segunda División club Juventud de Las Piedras.