From a well-established bureaucratic colonial family from spanish origins, He inherited a large fortune, which he increased considerably through very successful business and real estate activities.

[4] In response, the Marquis sent the king two letters in which he not only protested the mistreatment to which he was being subjected, but also stated that the disorder and misery of the viceroyalty was due to the incompetence and corruption of the viceregal administration.

[5] Probably due to the tension caused by a recent uprising in the northeast of the viceroyalty in 1781 – the Comuneros insurrection – the Marquis' gesture was poorly received at court, and from Spain came the order to imprison Lozano de Peralta, who At the beginning of 1787 he had to leave Santafé under arrest.

Although since 1790 he enjoyed freedom in Cartagena de Indias, he died on August 11, 1793, in said city, waiting for his situation to be resolved and thus be able to return to the capital of the viceroyalty.

He had several of his children, including José María Lozano, second Marquis of San Jorge and inhabitant of the house that today bears the name of said noble title.