He is the former president of Nicaraguan business chamber, the Superior Council for Private Enterprise (COSEP), where he worked closely with Nicaraguan President Daniel Ortega as a strong proponent of the "consensus model" that gave the business community a large degree of influence over economic policy in exchange for supporting Ortega.

However, the consensus broke down over social security reforms and human rights abuses in April 2018 and Aguerri became a vocal critic of Ortega.

[2] He worked at Banco Uno for a time and then in 2005 was introduced to the Chamber of Commerce by his high school classmate Sucre Frech Zablah (son of the famous sports announcer).

[1] Aguerri became immediately successful: within nine months he was president of the chamber and vice-president of the Superior Council for Private Enterprise (COSEP), the leading Nicaraguan association representing the interests of the business sector.

However the consensus model broke down on 16 April 2018 when the government announced a unilateral overhaul of social security and its associated tax structure; business sector representatives withdrew in protest for the failure to consult them.

[2] He called for Ortega to step down and commented that the business community shared some responsibility for the crisis, having focused on their economic priorities while ignoring issues around democracy and civic institutions.

[5] On 7 September 2019, FSLN shot at his car as he left León, where he traveled as a member of the Civic Alliance to escort a radio owner who had been subject to confiscation.