"On March 3, 1989, only 4 days after the death of Teófilo Forero, Antequera was murdered in the El Dorado International Airport in Bogotá, while he was heading to Barranquilla,[5] an attack in which the then-presidential pre-candidate of the Liberal Party, Ernesto Samper, was wounded with 11 bullets from an Ingram 9 mm submachine gun, Antequera was shot 28 times by a hitman identified as Luis Fernando Mona Hincapié, a 20-year old from Medellín, who was later killed by Administrative Department of Security (DAS) bodyguards.

[6] His assassination was followed by protests and riots, in rejection of the refusal of the then mayor of Bogotá, Andrés Pastrana, to allow a collective farewell ceremony for the slain political leader.

[7][8] Some investigations carried out by the Analysis and Context Unit of the Office of the Attorney General of Colombia pointed to an alliance between paramilitary groups, state security agencies and drug traffickers as responsible for the murder.

Particularly, the links of Antequera's crime with the murders of Bernardo Jaramillo Ossa, and Carlos Pizarro have been investigated due to the coincidences with both, and it is even linked to the crime of Luis Carlos Galán that occurred five months later, based on the declarations Jhon Jairo Velásquez Vásquez, alias Popeye, a hitman for the Medillín Cartel.

Likewise, investigations carried out by the prosecutor's office since 1992 established that Luis Fernando Mona Hincapié had been a co-worker of cousins Andrés Arturo and Gerardo Gutiérrez, known to be the hitmen who shot Jaramillo and Pizarro respectively, who worked alongside Mona Hincapié in a billiard cue factory in Medellín were allegedly recruited to commit the assassinations by a man identified as Héctor de Jesús Echeverría Acevedo, a possible hitman boss of a criminal group identified as La Oficina.