José María Medina Castejón (8 September 1826 – 1878) served as the President of Honduras three times during the 1860s and 1870s.

[citation needed] At the age of 18 Medina joined the Honduran Army, and in the same year of 1844 fought in Nicaragua as a junior officer against William Walker's attempts to conquer Central America.

He served as an Official member of the Central American Joint Chiefs of Staff from July 1856 to May 1857.

[citation needed] His first term in office was served as a temporary Acting President between 1 September and 31 December 1863.

He provisionally served a third time between 12 and 27 August 1876, and was later arrested for treason and executed by firing squad in 1878 in Santa Rosa de Copán.