The elder Keeler had been born in New Jersey and worked as a stonemason in New York City and Philadelphia.
When Joseph was two his family moved to Provo to avoid the anticipated destruction of Salt Lake by Johnston's Army.
Martha like her husband was active in the LDS Church and was involved in the writing of the First Relief Society Manual.
Keeler was scheduled to begin work at BYA the day after the Lewis Building (which he had been one of the builders of) burned to the ground.
Keeler later went to Poughkeepsie, New York where he received a Master of Accounts degree from Eastman Business College.
Keeler wrote a book on the Aaronic Priesthood which in 1904 was used as the first Aaronic Priesthood manual in the LDS Church, Foundation Stones of the Earth, A Concordance of the Doctrine and Covenants, The Student's Guide to Bookkeeping and also a book entitled First Steps in Church Government.
In 1901 Keeler became first counselor to David John in the presidency of the Utah Stake, which had been reduced to just the city of Provo.