This remedy was described by Brandreth in a paper entitled On the Advantages arising from the Topical Application of Cold Water and Vinegar in Typhus and On the Use of Large Doses of Opium in certain cases.

He was a man of wide and various reading, and possessed a most accurate and tenacious memory, which he attributed to his habit of depending on it without referring to notes.

The Infirmary had 84 beds, and Joseph and other senior physicians and surgeons gave their services free of charge.

[1] This remedy he described in a paper On the Advantages arising from the Topical Application of Cold Water and Vinegar in Typhus, and on the Use of Large Doses of Opium in certain Cases.

The most famous physician in Liverpool at this time was James Currie, who also led a distinctive life devoted to the services of mankind.

HON EDWARD EARL & ELIZABETH COUNTESS of DERBY He was many years first Physician to the LIVERPOOL INFIRMARY And zealously exerted himself in establishing the DISPENSARY.