Along with other prominent Gozitans, Cefai was known for his promotion of the interests of the island of Gozo where he was born on October 28, 1921.
In 1947, together with other prominent Gozitans including Francesco Masini, he stood as candidate in the elections in the name of the newly founded Gozo Party and was elected member of the Legislative Assembly.
During that legislature Cefai was active in the defence and promotion of Gozitan interests.
Cefai remained a member of that legislature till the dissolution of the same in June 1950.
In February 1973, Cefai was nominated by the Government as Assistant Secretary for Gozo Affairs and subsequently in 1974 he was nominated for Secretary of Gozo Affairs, a post which he continued to occupy till 1981.