Grech was born in Balzan, Colony of Malta, on 10 December 1948.

He was ordained a priest on 30 November 1974 in his home town, before returning to Melbourne to take up parish duties.

On 8 March 2001, he was appointed the Bishop of Sandhurst, based in the regional Victorian city of Bendigo.

He was installed on 27 April and served in that position until his death from a blood disorder on 28 December 2010.

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