He was brother of William Skelton, and became an engraver specialising in topographical and antiquarian subjects.
A subscription was raised for him in Oxford in 1856 on account of poverty,[2] and he was granted a place in the Charterhouse in 1859, where he died in 1871.
He was elected a Fellow of the Society of Antiquaries of London in 1825; his name disappears from its lists in 1844.
At Oxford he published Oxonia Antiqua Illustrata (1823); Antiquities of Oxfordshire, from drawings by F. Mackenzie (1823); Pietas Oxoniensis, or Records of Oxford Founders (1828); and Engraved Illustrations of Antient Arms and Armour from the Collection at Goodrich Court from the Drawings, and with the Descriptions of Dr. Meyrick, (2 volumes, 1830).
He also engraved the heading to the Oxford almanacks for the years 1815 to 1831, from drawings by F. Mackenzie and C. Wild; and executed a set of fifty-six etchings of the antiquities of Bristol after Hugh O'Neill, 1825.