In 1845 he founded the Deutsche Eisenbahnschienen-Compagnie auf Actien (German Railway Rail joint stock company).
It published several editions of the Bible, works of classical literature ("Miniatur-Bibliothek der deutschen Classiker", "Groschen-Bibliothek"), the world in pictures on steel engravings ("Meyers Universum", 1833–61, 17 volumes in 12 languages with 80,000 subscribers all over Europe), and an encyclopaedia, ("das Grosse Conversations-Lexikon für die gebildeten Stände"; see Meyers Konversations-Lexikon, 1839–55, 52 volumes).
[2] He became involved in cartography, producing many atlases with steel-engraved maps printed from steel plates, including Meyer's Groẞer Hand-Atlas (1843-1860).
[1]: 458/2 In 1830, inspired by new of the July Revolution in France, Meyer founded newspapers that promoted the liberal ideals of the revolutionaries.
[1]: 461/1 His publishing and other businesses prospered, and by 1910 his grandsons constituted the richest family in the Saxon territories, with more total wealth than the King of Saxony.