She served as Ambassador and Deputy U.S. Trade Representative under President George Bush, covering all Asia, Africa and Intellectual Property, Technology and Agriculture from 2001-2005.

In the role she introduced the first block chain to deliver food and cash to war zones such as Syria, and successfully negotiated access into Somalia, North Korea and Libya.

On July 26, 2021 she was appointed President[4] of Canoo (NASDAQ: GOEV) an electric vehicle startup based in Los Angeles with manufacturing facilities in Oklahoma City, OK. Sheeran was born in Orange, New Jersey, and is one of six siblings.

She pioneered new initiatives such as the African Risk Capacity (ARC), the first disaster insurance model for Africa, and “Purchase for Progress” in more than a dozen nations and conflict zones.

Ms. Sheeran chaired the UN High Level Committee on Management for two terms, leading more than 40 UN entities in a series of historic reforms, from the adoption of International Public Accounting Standards (IPSAS), to enacting world-class agreements on transparency, ethics, whistle-blowing, financial disclosure and technology.

[13] Pedro Medrano Rojas, a Chilean diplomat, originally led the UN's cholera response, and left in 2015 upset that the international community failed to "acknowledge the fact that we have in Haiti the largest epidemic in the Western Hemisphere.

She headed a host of high-level bilateral or multilateral economic dialogues with the European Union, China, India, Japan, Iraq, Afghanistan, and many others.

One of her legacy projects was fighting global counterfeiting, creating STOP – Strategy Targeting Organized Piracy and the protection of Intellectual Property.

She helped bring to a successful conclusion the landmark U.S.-Australia Free Trade Agreement (FTA), which is expected to increase U.S. exports to Australia by $2 billion a year.

Before joining USTR, Sheeran was managing director of Starpoint Solutions, a Wall Street technology firm that works with Fortune 500 clients.

Sheeran also served as President and Chief Executive Officer of Empower America, where she developed its agenda of trade policy, technology policy, education reform, and tax reform, and advancing the agenda of Empowerment Economics to transform America's poorest cities and regions under the leadership of Jack Kemp and Ambassador Jeane Kirkpatrick.

[5] During her tenure as managing editor of The Washington Times, she appeared as a commentator on programs such as Nightline, Fox News, The McLaughlin Group, The Diane Rehm Show, and CNN.

[15] Ambassador Sheeran serves on the boards of Capital Group funds, which manages more than $2.5 trillion in global investments; Vestergaard International, which has delivered 1 billion high tech nets to prevent deaths from malaria; Lifestraw, a pioneer in access to safe water; Sceye, the world’s first stationary stratospheric vessel and the Business Council for International Understanding.

She also serves on the Board of Directors, and as co-chair of the Finance & Human Resources Committee, of the Alliance for a Green Revolution in Africa (AGRA), founded through a partnership between the Rockefeller Foundation and the Bill & Melinda Gates Foundation in 2006 in response to a call from former UN Secretary-General Kofi Annan, who said the time had come for African farmers to wage a “uniquely African Green Revolution.” Sheeran is a member of the Council on Foreign Relations.