He has received acting awards including the James Pendleton Foundation Prize for Outstanding Achievement in Performance and the Judith & Milton R. Stark Scholarship.

[citation needed] He played the lead role of Nate Solomon in NBC's 2005 sitcom Committed.

In 2006, Cooke co-starred in the film Wasted as Dixon, alongside Eddie Kaye Thomas and Kip Pardue.

[5] Cooke starred as Andy in the 2010 comedy Group Sex, alongside Greg Grunberg and Odette Yustman.

Cooke played the lead role as Ron in the 2008 direct-to-DVD film Bachelor Party 2: The Last Temptation.

In 2016, Cooke was cast in the La Jolla Playhouse premiere of Pulitzer Prize winner and Tony Award nominee Ayad Akhtar's Junk: The Golden Age of Debt as "Robert Merkin."