Harris signed as an undrafted free agent with the Atlanta Falcons on April 26, 2012, following the 2012 NFL draft.

[2] He was selected over veteran Joe Zelenka in the pre-season, when the roster was cut down to 53 players.

[4] In the 2016 season, Harris and the Falcons reached Super Bowl LI, where they faced the New England Patriots on February 5, 2017, losing 28–34 in overtime.

[8] On December 22, 2021, Harris was selected to his first Pro Bowl,[9] and would be later awarded second-team All-Pro for his work during the 2021 season.

[10] On March 16, 2022, Harris signed a four-year, $5.6 million contract with the Los Angeles Chargers.