His other television credits include Chicago P.D., The Other Two, AJ and the Queen, Orange Is the New Black, and She-Hulk: Attorney at Law, while his other theatrical credits include the musicals Lysistrata Jones and Dogfight, and the slasher horror film Scream VI.

[8][9] From 2009 to 2011, Segarra portrayed a main role of Hector Ruiz on the PBS Kids Go television series The Electric Company.

[15] Segarra originated the role of Emilio Estefan in the musical On Your Feet!, which opened at the Marquis Theater on Broadway on November 5, 2015.

[20] Since January 2019, Segarra has been a recurring cast member on The Other Two, a comedy television series on HBO Max.

[21][22] In December, he recurred on The Moodys as Marco, a "commodities broker with exquisite phone skills.

[25] That same year, Segarra appeared as a special agent during the third season of the crime drama series FBI and starred as a pastor in the musical film Christmas on the Square.