On October 6 of that year, Camacho fought undefeated (2-0-1) Jose Luis De Jesus in Guaynabo, winning by a four-round split decision.

On August 4, 1990, Camacho fought Miguel Santos, 1-7-1, at Pedrin Zorrilla Coliseum in San Juan, winning by technical knockout in four rounds.

One month and eleven days later, on September 15, he returned to action at the same coliseum, this time meeting Julio Cesar Acevedo, 3-3-1, and winning by eight round unanimous decision.

Camacho finished 1990 by fighting Julio Cesar Acevedo in a rematch, this time for the vacant Puerto Rican Light-Flyweight title.

Camacho then fought well-known Puerto Rican Angel Rosario, who had just come off a world title fight loss to Jose Ruiz.

Despite having a negative win–loss record, after his knockout win over Jesus Vera, he was given an opportunity to fight Camacho for the World Boxing Organization's vacant Light-Flyweight title.

These included a challenge of World Boxing Board Flyweight champion Marc Johnson by knockout in eight, exactly one year after the Carbajal fight, on July 15, 1995, at the Great Western Forum in Inglewood, California, (as part of the Saman Sorjaturong-Humberto Gonzalez undercard), a challenge of World Boxing Union Light-Flyweight champion Nungdiaw Sakcharuporn on January 27, 1996, at the Bansaen Stadium, Chonburi, Thailand, when he was beaten by ninth-round technical knockout, and a loss to WBA Fedelatin Light-Flyweight monarch Gilberto Gonzalez, 7-1-1, by a fifth-round technical knockout at Miami, Florida, March 23, 1996.

This turned out to be Camacho's last career victory, and he subsequently lost to Leo Gamez by an eight-round knockout at Roberto Clemente Coliseum in San Juan, May 29, 1999, for the WBA's interim Super-Flyweight title, then to Gerson Guerrero by a first-round knockout at Fantasy Springs Casino in Indio, California, for the vacant North American Boxing Federation's Flyweight title on May 19, 2001, and to Miguel Del Valle in a rematch, May 25, 2002, at the Acropolis in Manati, Puerto Rico, by a twelve-round unanimous decision for the WBC's CABOFE Flyweight championship.