The Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology is a monthly peer-reviewed scientific journal of comparative physiology.

It was established in 1984, when it was split off from the Journal of Comparative Physiology.

The editor-in-chief is Gerhard Heldmaier (Universität Marburg).

The journal become electronic only in 2017.

The journal is indexed and abstracted in the following bibliographic databases:[1] According to the Journal Citation Reports, the journal has a 2017 impact factor of 2.517.